The National Academies of Sciences, Engineering and Medicine

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Registration is now open for the first meeting of the International Commission on Clinical Use of Heritable Human Genome Editing

The international commission has been convened by the U.S. National Academy of Medicine (NAM), the U.S. National Academy of Sciences (NAS), and the Royal Society of the U.K., with the participation of science and medical academies around the world, to develop a framework for scientists, clinicians, and regulatory authorities to consider when assessing potential clinical applications of human germline genome editing. The framework will identify a number of scientific, medical, and ethical requirements that should be considered, and could inform the development of a potential pathway from research to clinical use — if society concludes that heritable human genome editing applications are acceptable.

The first meeting of the commission will take place at the National Academy of Sciences Building in Washington, DC on August 13, 2019. View agenda (204 KB, PDF).

The event will be webcast. Registration is required to attend the event in person and to view the webcast.

Members of the press should register by contacting the National Academies’ Office of News and Public Information at or 202-334-2138.


The commission is the latest action from the international science community to address issues around human genome editing. It follows the Second International Summit on Human Genome Editing — held last November in Hong Kong by NAS, NAM, the Royal Society, and the Academy of Sciences of Hong Kong. The topic became a focus of global attention when a scientist from China revealed at the summit that as a result of his research, twins had been born whose embryonic genomes had been edited. The scientist was widely condemned by the global scientific community for violating long-standing scientific principles and ethical norms.

The U.S. National Academies and the Royal Society are the secretariat of the commission, which includes representatives from 10 nations. Kay Davies, professor of genetics at the MDUK Oxford Neuromuscular Centre at the University of Oxford, England, and Richard Lifton, president of the Rockefeller University in New York City, are co-chairs of the commission. The commission will hold one additional meeting and an international workshop, and will also issue a call for public input to inform their work. A final report from the commission is expected to be issued in the spring of 2020.   


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